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The Lab Me crucial at-home male hormones test helps assess baseline levels before hormone replacement therapy, or for estrogen dominance, hypogonadism, andropause, fatigue, low libido, erectile dysfunction, infertility, and adrenal dysfunction. Also ideal for monitoring HRT dosing.
Includes licensed physician reviewed results and recommendations on improvement. You are also allowed to ask our medical team any questions you may have regarding your results for no additional charge.
If purchasing for two people, it’s required to create their account to order.
All Lab Me tests are performed by high-complexity CLIA certified and CAP-accredited laboratories.
As men age, their levels of testosterone begin to decline, usually beginning
around the mid-40s. This heralds what is commonly known as andropause,
the male counterpart to menopause. While this is a natural part of aging, the decline in testosterone production by the testes can be more precipitous in some men than others.
Using Lab Me's at-home male hormones test gives you insight into such issues.
Excessive weight gain, stress, lack of exercise, and many medications further contribute to a man’s ability to manufacture testosterone, resulting in even lower testosterone levels and leading to symptoms of andropause.
These symptoms may include low libido, irritability, depression, loss of muscle mass and strength, weight gain, metabolic syndrome, erectile dysfunction, sleep disturbances, osteoporosis, and adverse changes in the blood lipid profile.
However, while hormone replacement therapy is certainly an option, the solution to the problem may not be a simple case of restoring testosterone levels. For example, some practitioners find that testosterone therapy may be of little benefit unless problems affecting cortisol production are addressed first.
The body’s response to stress is mediated by increased cortisol production, and this prepares the body for “fight or flight” by shutting down other processes, including testosterone production.
Correcting disorders such as adrenal fatigue or chronic stress may therefore lead to improved testosterone levels and resolve symptoms, without requiring testosterone therapy.
Increasing cortisol levels, along with several other endocrine changes, have been reported in men, highlighting the need to obtain a complete hormone profile such as this test, before initiating any hormone replacement.
Testosterone (ng/dl)
Premenopausal - luteal: 18-39
Postmenopausal: 13-38
Postmenopausal - testosterone replacement:
29-224
DHEA-Sulfate
17 - 207 ng/dL
Estradiol
Premenopausal - luteal 51-302 ug/dL
Premenopausal - early follicular 30-92 ug/dL
Postmenopausal <10-26 ug/dL
Postmenopausal - estrogen replacement 32-472 ug/dL
Progesterone (ng/ml)
Premenopausal - luteal: 4.3-25.3 <0.1-0.9 0.5-4.3 5.2-65.3
Postmenopausal: <0.1-0.9 0.5-4.3 5.2-65.3
Oral Pg (100-300 mg): 0.5-4.3
Topical Pg (10-30 mg): 5.2-65.3
Cortisol (ug/ml)
Morning: 9.1-19.6
Evening/night: 3.3-8.9
Estradiol (E2)
Estradiol is an estrogen and the primary sex hormone for females. It is important in regulating the reproductive cycles for females. It is released from ovaries and adrenal glands and plays a major role in the growth of women's reproductive tissues, including breasts, uterus, fallopian tubes, and vagina throughout life stages. This also affects other tissues including bone, fat, skin, liver, and brain. When assessing menopausal symptoms that may include hot flashes, mood disturbances, and aging skin, it is important to compare the relationship between estradiol and progesterone.
Males do have estradiol in their bodies but the amount compared to females is much lower. Estradiol is released from the testes and adrenal glands. Since males lack female anatomy, they must generate estrogen through a process involving aromatase, an enzyme that converts testosterone into estradiol. Estradiol has been shown in vitro to stop cell destruction, but its clinical importance in male sexual function and growth is lower than in females.
Progesterone (Pg)
Progesterone is a female hormone, released during ovulation by the ovaries. When a sperm fertilizes an egg, progesterone helps to prepare the uterus lining (endometrium) for the egg. If the egg is not fertilized, the level of progesterone decreases, and menstrual bleeding starts. During pregnancy the placenta releases high levels of progesterone, beginning at the end of the first trimester and continuing through birth. Pregnant women have progesterone levels almost 10 times higher than females who are not pregnant. Additionally, certain forms of cancer trigger elevated levels of progesterone in both men and women.
Testosterone
Testosterone is the primary sex hormone and anabolic steroid for males. Testosterone plays a key role in male reproductive tissue production, such as testes and prostate, as well as promoting secondary sexual characteristics, such as increased muscle and bone mass, and body hair growth. Female ovaries do produce testosterone in much smaller amounts compared to males. Testosterone development begins to increase dramatically during puberty and starts declining after age 30 or so.
DHEA Sulfate
DHEA sulfate is an androgen (male sex hormone) that is present in the blood of both men and women. It assists in the development of male secondary sexual characteristics at puberty and can be metabolized into testosterone and androstenedione (more potent androgens), or changed into estrogen (a female hormone). The outer layer of the adrenal glands, the adrenal cortex, is responsible for producing DHEA sulfate, while smaller amounts are produced in the testes and ovaries. Dehydroepiandrosterone sulfate secretion is controlled by the pituitary hormone adrenocorticotropic hormone (ACTH) and other pituitary factors. Since DHEA,s is primarily produced by the adrenal glands, it is a strong marker for adrenal function. Cancers, adrenal tumors, and hyperplasia can lead to the overproduction of DHEA sulfate. While elevated levels may not be noticed in adult men, they can lead to visible symptoms of virilization and amenorrhea.
Cortisol
Cortisol, the major adrenal glucocorticoid steroid hormone, is usually under feedback control by pituitary ACTH and the hypothalamus. Causes of low cortisol include pituitary failure or destruction, with resultant loss of ACTH to stimulate the adrenal, and metabolic errors or destruction of the adrenal gland itself (adrenogenital syndromes, tuberculosis, histoplasmosis). The diagnosis of hypoadrenalism usually requires confirmation with ACTH stimulation, due to the circadian rhythms of cortisol and other factors. Causes of increased cortisol, which may initially present as simply a loss of normal diurnal variation, include pituitary overproduction of ACTH, production of ACTH by a tumor (notably oat cell cancers), and adrenal adenomas.
Preparation: 10-12 hours fasting is required. Avoid anti-aging/anti-wrinkle facial creams for 3 days prior to testing as they may contain undisclosed hormones.
Test Results: 7-8 Days once the lab receives the specimen. May take longer based on weather, holiday or lab delays.
